Memantine led to functional improvement and reduced care dependence in severe dementia
نویسندگان
چکیده
منابع مشابه
Galantamine-memantine combination effective in dementia: Translate to dementia praecox?
Cholinergic and glutamatergic systems, alpha-7 nicotinic acetylcholine receptor (α-7nAChR) and N-methyl-D-aspartate (NMDA) receptor are strongly implicated with cognitive impairments in Alzheimer's disease (AD). Donepezil, a frequently used drug in the treatment of AD, is only an acetylcholinesterase inhibitor (AChEI), whereas galantamine is an AChEI and a positive allosteric modulator of the α...
متن کاملReduced Functional Dependence Graph and Its Applications
Functional dependence graph (FDG) is an important class of directed graph that captures the dominance relationship among a set of variables. FDG is frequently used in calculating network coding capacity bounds. However, the order of FDG is usually much larger than the original network and the computational complexity of many bounds grows exponentially with the order of FDG. In this paper, we in...
متن کاملwhether hospital accreditation has led to improvement of care quality in iran or not?
the most important mission of hospitals is to provide appropriate and high quality care for patients. different methods and models have been used to assess the quality of care. one conventional model used recently in many countries is the accreditation model which has been efficient in developing structural, process, and outcome standards. accreditation is a systematic process carried out based...
متن کاملMemantine: efficacy and safety in mild-to-severe Alzheimer’s disease
Alzheimer's disease (AD) is the most common cause of dementia, accounting for 25 million cases worldwide. Until recently, the pharmacotherapy of AD was limited to the use of cholinesterase inhibitors (ChEIs) that are approved only for the mild to moderate stages of the illness. Memantine, an NMDA receptor antagonist has been found to be effective, both as monotherapy and in combination with don...
متن کاملPM323. Cognitive function improvement in alcoholic dementia after 12 week memantine treatment
s | 15 Conclusion: This is a first report associating DNA methylation signature with abstinence in alcoholics treated with acamprosate. Future studies are needed to investigate the value of this association as a potential biomarker of acamprosate response in treatment-seeking alcoholics. PM322 The risk factors of low bone mineral density in male alcoholic patients: cross-sectional study Tadasu ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Evidence-Based Mental Health
سال: 1999
ISSN: 1362-0347
DOI: 10.1136/ebmh.2.4.113